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Winston Peki

CBG VS CBD: Similarities, Differences, and Use Cases

Today, you'll learn about CBD and CBG, specifically the: health benefits, side effects, and, interactions of both. We reviewed studies that describe the biochemistry and effects of both CBD and CBG. Both these compounds produce therapeutic benefits by interacting with numerous ... Continue Reading

How Does A Dry Herb Vaporizer Work?

Today you're going to learn how dry herb vaporizers work. Maybe you're still on the fence about dry herb vaping, and you're not sure whether it's safe or not. Or maybe you're a vaping geek like me, and want to understand the technicalities of dry herb vaporizers. Understand how your dry ... Continue Reading

CBN VS CBD: Similarities, Differences, and Use Cases

Today, we’re going to discuss CBN and CBD, and their: similarities, differences, and; use cases. We reviewed 21 studies and found that CBD and CBN are both similar and different in many ways. By reading this article, you will be able to get a better understanding of how CBN and CBD ... Continue Reading

4 Best Dry Herb Vape Pens in 2023

Today you’re getting a list of the best dry herb vape pens in 2023.With a total of 100+ dry herb vaporizers reviewed, including 23 vape pens, over a period of 6+ years, on metrics like: Safety; Extraction-speed; Vapor quality; Ease of use, and many more; You can be sure ... Continue Reading

CBD for Migraines: Scientific Evidence and Mechanism of Action

Anecdotal evidence shows that CBD can be helpful for migraine. But is there any scientific evidence backing up the anecdotal? Today, we’re going to look at whether there’s any evidence that supports the use of CBD for migraines. We’re also going to use scientific evidence and anecdotal ... Continue Reading

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© Copyright www.herbonaut.com · All Rights Reserved. The content on this website is for informational purposes only and is not intended as medical advice. Medical advice should always be obtained from a qualified medical professional for any health conditions or symptoms associated with them. Every possible effort has been made in preparing and researching this material. We make no warranties with respect to the accuracy, applicability of its contents or any omissions.

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In no way do these affiliate links influence the products that we recommend. This website is first and foremost built on trust and honesty. We are 100% convinced that you’ll come to the same conclusion by following up on our advice. In case you feel our advice was not what you expected, please do contact us, as we would love to hear from you and have a friendly discussion with you about your experiences and findings!

Scientific References

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Baswan, S. M., Klosner, A. E., Glynn, K., Rajgopal, A., Malik, K., Yim, S., & Stern, N. (2020). Therapeutic potential of cannabidiol (CBD) for skin health and disorders. Clinical, Cosmetic and Investigational Dermatology, 13, 927–942. https://doi.org/10.2147/ccid.s286411

Borrelli, F., Fasolino, I., Romano, B., Capasso, R., Maiello, F., Coppola, D., Orlando, P., Battista, G., Pagano, E., Di Marzo, V., & Izzo, A. A. (2013). Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease. Biochemical Pharmacology, 85(9), 1306–1316. https://doi.org/10.1016/j.bcp.2013.01.017

Borrelli, F., Pagano, E., Romano, B., Panzera, S., Maiello, F., Coppola, D., De Petrocellis, L., Buono, L., Orlando, P., & Izzo, A. A. (2014). Colon carcinogenesis is inhibited by the TRPM8 antagonist Cannabigerol, a cannabis-derived non-psychotropic cannabinoid. Carcinogenesis, 35(12), 2787–2797. https://doi.org/10.1093/carcin/bgu205

De Petrocellis, L., Ligresti, A., Moriello, A. S., Allarà, M., Bisogno, T., Petrosino, S., Stott, C. G., & Di Marzo, V. (2011). Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. British Journal of Pharmacology, 163(7), 1479–1494. https://doi.org/10.1111/j.1476-5381.2010.01166.x

Díaz-Alonso, J., Paraíso-Luna, J., Navarrete, C., del Río, C., Cantarero, I., Palomares, B., Aguareles, J., Fernández-Ruiz, J., Bellido, M. L., Pollastro, F., Appendino, G., Calzado, M. A., Galve-Roperh, I., & Muñoz, E. (2016). VCE-003.2, a novel cannabigerol derivative, enhances neuronal progenitor cell survival and alleviates symptomatology in murine models of Huntington’s disease. Scientific Reports, 6(1). https://doi.org/10.1038/srep29789

Farrelly, A. M., Vlachou, S., & Grintzalis, K. (2021). Efficacy of phytocannabinoids in epilepsy treatment: Novel approaches and recent advances. International Journal of Environmental Research and Public Health, 18(8), 3993. https://doi.org/10.3390/ijerph18083993

Hill, A. J., Williams, C. M., Whalley, B. J., & Stephens, G. J. (2012). Phytocannabinoids as novel therapeutic agents in CNS disorders. Pharmacology & Therapeutics, 133(1), 79–97. https://doi.org/10.1016/j.pharmthera.2011.09.002

Iffland, K., & Grotenhermen, F. (2017). An update on safety and side effects of Cannabidiol: A review of Clinical Data and relevant animal studies. Cannabis and Cannabinoid Research, 2(1), 139–154. https://doi.org/10.1089/can.2016.0034

Klotz, K. A., Grob, D., Schönberger, J., Nakamura, L., Metternich, B., Schulze-Bonhage, A., & Jacobs, J. (2021). Effect of cannabidiol on interictal epileptiform activity and sleep architecture in children with intractable epilepsy: A prospective open-label study. CNS Drugs, 35(11), 1207–1215. https://doi.org/10.1007/s40263-021-00867-0

Mammana, S., Cavalli, E., Gugliandolo, A., Silvestro, S., Pollastro, F., Bramanti, P., & Mazzon, E. (2019). Could the combination of two non-psychotropic cannabinoids counteract neuroinflammation? effectiveness of cannabidiol associated with Cannabigerol. Medicina, 55(11), 747. https://doi.org/10.3390/medicina55110747

Nachnani, R., Raup-Konsavage, W. M., & Vrana, K. E. (2020). The pharmacological case for Cannabigerol. Journal of Pharmacology and Experimental Therapeutics, 376(2), 204–212. https://doi.org/10.1124/jpet.120.000340

O'Sullivan, S. E., Stevenson, C. W., & Laviolette, S. R. (2021). Could cannabidiol be a treatment for coronavirus disease-19-related anxiety disorders? Cannabis and Cannabinoid Research, 6(1), 7–18. https://doi.org/10.1089/can.2020.0102

Perez, E., Fernandez, J. R., Fitzgerald, C., Rouzard, K., Tamura, M., & Savile, C. (2022). In vitro and clinical evaluation of Cannabigerol (CBG) produced via yeast biosynthesis: A cannabinoid with a broad range of anti-inflammatory and skin health-boosting properties. Molecules, 27(2), 491. https://doi.org/10.3390/molecules27020491

Rock, E. M., Goodwin, J. M., Limebeer, C. L., Breuer, A., Pertwee, R. G., Mechoulam, R., & Parker, L. A. (2011). Interaction between non-psychotropic cannabinoids in marihuana: Effect of Cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews. Psychopharmacology, 215(3), 505–512. https://doi.org/10.1007/s00213-010-2157-4

Rock, E. M., Goodwin, J. M., Limebeer, C. L., Breuer, A., Pertwee, R. G., Mechoulam, R., & Parker, L. A. (2011). Interaction between non-psychotropic cannabinoids in marihuana: Effect of Cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and Shrews. Psychopharmacology, 215(3), 505–512. https://doi.org/10.1007/s00213-010-2157-4

Russo, E. B., Cuttler, C., Cooper, Z. D., Stueber, A., Whiteley, V. L., & Sexton, M. (2021). Survey of patients employing cannabigerol-predominant cannabis preparations: Perceived medical effects, adverse events, and withdrawal symptoms. Cannabis and Cannabinoid Research. https://doi.org/10.1089/can.2021.0058

Smeriglio, A., Giofrè, S. V., Galati, E. M., Monforte, M. T., Cicero, N., D'Angelo, V., Grassi, G., & Circosta, C. (2018). Inhibition of aldose reductase activity by chemotypes extracts with high content of cannabidiol or Cannabigerol. Fitoterapia, 127, 101–108. https://doi.org/10.1016/j.fitote.2018.02.002

Zagožen, M., Čerenak, A., & Kreft, S. (2020). Cannabigerol and cannabichromene in Cannabis sativa L. Acta Pharmaceutica, 71(3), 355–364. https://doi.org/10.2478/acph-2021-0021

Thakkar K, Ruan CH, Ruan KH. Recent advances of cannabidiol studies in medicinal chemistry, pharmacology and therapeutics. Future Med Chem. 2021 Nov;13(22):1935-1937. doi: 10.4155/fmc-2021-0125. Epub 2021 Sep 29. PMID: 34583522.

Kaczocha, M., Rebecchi, M. J., Ralph, B. P., Teng, Y. H., Berger, W. T., Galbavy, W., Elmes, M. W., Glaser, S. T., Wang, L., Rizzo, R. C., Deutsch, D. G., & Ojima, I. (2014). Inhibition of fatty acid binding proteins elevates brain anandamide levels and produces analgesia. PloS one, 9(4), e94200. https://doi.org/10.1371/journal.pone.0094200

Science Based

This article is based on scientific studies, written by Winston Peki and fact-checked by experts.

Inside this article, you can find references to peer-reviewed scientific studies. The numbers in the parentheses (1, 2, …) are clickable links to these peer-reviewed scientific studies. In some cases, the link will give you direct access to the study, while in other cases if you want to read the full study, you either have to pay the publisher a fee or find a free version of the study elsewhere.

Herbonaut is a review and discussion platform that highly values honesty, integrity, and objectivity. We always strive to highlight the benefits, as well as the risks of a specific product or service.

Any topic can be approached from various angles, at Herbonaut we strive to highlight all these angles and will often examine and compare research with contradicting results.