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Science Based 9

By

Winston Peki

5 Best Full-Spectrum CBD Oils Reviewed and Compared (In 2023)

Affiliate disclosure

Best Full-Spectrum CBD OilToday, you’re getting a list of the best full-spectrum CBD oils that you can currently buy.

Let me start by saying:

Full-spectrum CBD oils are the most effective CBD products, period.

Today you’ll not only learn why they’re the most effective CBD products…

But you’ll learn:

  • How to verify whether a CBD oil is truly full-spectrum, and;
  • How to estimate the effectiveness of a full-spectrum oil without even trying it.

Let’s get started.

Quickly go to…

  1. #1 Receptra Naturals Serious Rest & Seriously Relax (Highest Full-Spectrum Ratio)
  2. #2 R+R Medicinals Full-Spectrum Tincture (Best Value)
  3. #3 NuLeaf Naturals Full-Spectrum CBD Oil (Most Consistent Cannabinoid- and Terpene-Profiles)
  4. #4 Charlotte’s Web Original Formula (Widest Cannabinoid-Profile)
  5. #5 Lazarus Naturals Full-Spectrum, High-Potency Tincture (Most Affordable)

Our Review Process Rating Full-Spectrum CBD Oils

The two most important metrics for rating full-spectrum CBD oil are:

  • how many different cannabinoids and terpenes are present in the oil, and,
  • In what concentrations. This is expressed in the ratio of CBD to other hemp-derived cannabinoids and terpenes. Also called ‘full-spectrum ratio’.

‘Full-spectrum’ means that the oil contains the full spectrum of cannabinoids and terpenes. But only those that are naturally found in hemp plants.

A true full-spectrum CBD oil has:

  • a wide variety of hemp-derived cannabinoids and terpenes, and,
  • in detectable concentrations.

The higher:

  • the number of cannabinoids and terpenes in a CBD oil, and,
  • the higher the concentrations,

the more ‘full-spectrum’ a CBD oil is.

When rating full-spectrum CBD products, the cannabinoid- and terpene-profile have the most weight. Even more so than in our regular CBD oil reviews.

Yes, a full-spectrum CBD oil also always contains small concentrations of THC.

Some people should avoid THC altogether. But most people benefit from having small concentrations of THC inside their CBD product. This is because it’s likely that CBD and THC have synergistic effects (1, 2).

1. Receptra Naturals Serious Rest & Seriously Relax (Highest Full-Spectrum Ratio)

Receptra Naturals Serious RestWhile all Receptra Naturals CBD oils score very high on both full-spectrum ratings:

  • The presence of a wide variety of hemp-derived cannabinoids and terpenes, and;
  • The presence of the cannabinoids and terpenes in high concentrations,

Two oil products score especially high on these metrics:

  • Receptra Naturals Serious Rest, and;
  • Receptra Naturals Seriously Relax.

When we check how many hemp-derived cannabinoids and terpenes are present in these products at detectable levels…

We can’t but conclude these are the absolute best full-spectrum CBD oils.

Serious Rest contains:

  • 8 different cannabinoids in detectable levels, with 2.75% CBD, and;
  • 8 different terpenes in detectable levels.

Seriously Relax contains:

  • 6 different cannabinoids in detectable levels, with 2.8% CBD, and;
  • 13 different terpenes in detectable levels.

The CBD to other cannabinoids + terpenes ratios are as follows:

  • Serious Rest > for every 1mg of CBD you will take 0.38mg of minor cannabinoids and terpenes;
  • Seriously Relax > for every 1mg of CBD you will take 0.55mg of minor cannabinoids and terpenes.

All these metrics are significantly higher than the average of our reviewed products.

But also, when it comes to other review metrics like:

  • transparency, and,
  • value,

Receptra Naturals scores higher than the average.

Every Receptra Naturals product comes with a QR code that links to a third-party lab-test report. Inside this report you can find all test results for that specific production batch. These are full-panel tests, including heavy metals, residual solvents, pesticides, and microbiological tests.

It doesn’t get more transparent than this.

Looking at how much CBD you get per dollar, Receptra Naturals products are less affordable than the average.

But when you take into account minor cannabinoids and terpenes, you get more than the average.

Also, you can’t compare the price of a full-spectrum product like this one to most CBD products.

It would be like comparing a vitamin C pill (the average CBD product) to blueberries. Blueberries (this oil) contain vitamin C, plus hundreds of other beneficial compounds.

Buy Receptra N. Full-Spectrum Oil

Full Review Receptra Naturals

The next option on the list, however, will provide even more value per dollar.

2. R+R Medicinals Full-Spectrum Tincture (Best Value)

R+R MedicinalsPound for pound, R+R Medicinals is the best value-for-money CBD brand out there.

While you can find brands that provide even more CBD per dollar than R+R Medicinals…

When it comes to full-spectrum CBD products…

There are no brands that provide more ‘CBD + minor cannabinoids and terpenes per dollar’ than R+R Medicinals.

Let’s take a look at the numbers.

R+R Medicinals full-spectrum CBD oils come in three strengths. But we are only interested in the 1000 and 2500mg strengths (the middle and the highest strength).

The 1000mg full-spectrum oil contains:

  • 7 different cannabinoids in detectable levels (3.8% CBD);
  • 6 different terpenes in detectable levels.

The 2500mg full-spectrum oil contains:

  • 7 different cannabinoids in detectable levels (9.3% CBD);
  • 13 terpenes in detectable levels.

The number of terpenes and cannabinoids in these oils is higher than in most other oils.

The CBD to other cannabinoids + terpenes ratios are as follows:

  • 1000mg full-spectrum oil > for every 1mg of CBD you will take 0.16mg of minor cannabinoids and terpenes;
  • 2500mg full-spectrum oil > for every 1mg of CBD you will take 0.11mg of minor cannabinoids and terpenes.

This is lower than, for example, with Receptra Naturals products. But it’s still significantly higher than the average.

When we look at the terpene-profile we see the following:
 
It has a high concentration of terpenes. And many different terpenes.
 
Terpenes are only present inside the flower parts of the hemp plant (4). So we can conclude this product is mostly made from the flower parts.

When it comes to transparency, R+R Medicinals is as transparent as it gets. Every product comes with a QR code that links to a batch-based lab-test report. Inside the report you can find the usual: cannabinoid-profile, terpene-profile, and contaminant tests.

Price is where R+R Medicinals full-spectrum oils shine. You get almost double the amount full-spectrum CBD compared to other premium brands.

Especially when you get the stronger 2500mg bottle, the value is insane. With that bottle, you get 25.7mg CBD per dollar (the average is 14.6mg). And keep in mind that this 25.7mg CBD is within a full-spectrum context.

Sure, you can find cheaper CBD products. But you won’t find cheaper CBD products that truly classify as full-spectrum.

Buy R+R Meds Full-Spectrum Oil

Full Review R+R Medicinals

Next up…

3. NuLeaf Naturals Full-Spectrum CBD Oil (Most Consistent Cannabinoid- and Terpene-Profiles)

NuLeaf Naturals is one of the most trusted brands in the CBD world.

It’s one of the older CBD brands. They’re active since 2014. Ever since, they have a trustworthy reputation as a full-spectrum CBD brand.

Full-spectrum cannabinoid products are literally all they sell.

And when it comes to the quality of their full-spectrum products…

I can only speak good about it.

Every NuLeaf Naturals cannabinoid product comes with many cannabinoids and terpenes.

The best part?

Their products always come with consistent cannabinoid- and terpene-profiles. It’s consistency across time, across batches, and across products. NuLeaf Naturals is a very consistent brand.

Let’s take a look at the stats of their full-spectrum CBD oil:

  • 6 different cannabinoids in detectable levels (6.8% CBD);
  • 5 different terpenes in detectable levels.

The variety of cannabinoids and terpenes is a bit lower in this oil compared to the previous options.

You have to keep in mind that this oil probably contains a lot more compounds that are either:

  • Not tested for, or;
  • Only present in trace elements.

But the same holds true for the other oils on the list.

When we look at how many minor cannabinoids and terpenes you get per 1mg of CBD, we can see the following ratio:

  • For every 1mg of CBD, you get 0.13mg of minor cannabinoids and terpenes.

This is around the average for true full-spectrum oils.

There are oils that have more minor cannabinoids and terpenes per mg of CBD than NuLeaf Naturals oil. But a lot of them have added isolated cannabinoids.

Products that are a combination of isolated cannabinoids are not truly full-spectrum. Why? Because they don’t contain hundreds of other compounds that are present in hemp flower.

Transparency-wise NuLeaf Naturals is as transparent as it gets:

Third-party lab-test reports with full-panel testing for every production batch.

When we look at price we can see that NuLeaf Naturals is a bit more expensive than the average. Unless you get their bigger 3000mg or 6000mg bottles.

Buy NuLeaf N. Full-Spectrum Oil

Full Review NuLeaf Naturals

Up next…

4. Charlotte’s Web Original Formula (Widest Cannabinoid-Profile)

Charlotte's Web Original FormulaCharlotte’s Web is another premium full-spectrum CBD brand.

When it comes to their full-spectrum oils, you have two different options:

  • An ethanol-extracted oil called “Original Formula”, and;
  • A CO2-extracted oil called “60mg CBD/1ml”

Charlotte’s Web themselves classify their ethanol-extracted Original Formula as a terpene-dominant oil. And their CO2-extracted 60mg CBD/1ml as a cannabinoid-dominant oil.

So, which one of these oils is the better full-spectrum oil?

You first have to understand the importance of cannabinoids relative to terpenes.

Cannabinoids have more synergy between themselves than between them and terpenes (1, 2).

But that doesn’t exclude terpenes from having an important role in cannabis plant synergy (3).

The cannabinoid-profile has more weight in rating a full-spectrum oil. But terpenes have a lot of weight as well.

The cannabinoid-profiles of both products are similar. The terpene-profile is what differs.

Unfortunately, Charlotte’s Web doesn’t publish terpene-profiles of their products.

But based on:

  • their own words, and,
  • the fact that ethanol-extraction is better for preserving volatile compounds like monoterpenes (4),

it’s likely that the Original Formula contains more terpenes than the CO2-extracted oil.

Both products have a similar cannabinoid-profile. Terpenes give the edge to their Original Formula oil.

Let’s look at the stats.

Charlotte’s Web Original Formula contains:

  • 11 cannabinoids in detectable levels (5.7% CBD);
  • An unknown number of terpenes.

This is the oil with the most different cannabinoids in detectable levels.

Whether that’s because:

  • they use a more sensitive testing method,
  • simply test for more different cannabinoids, or,
  • his oil truly contains more different cannabinoids,

remains unclear.

Nonetheless, the stats don’t lie. Based on the lab-test reports, this oil has the widest cannabinoid-profile.

To calculate the ‘full-spectrum ratio’, we gave this oil an average terpene content of 0.2%. We don’t know the true terpene-content, but 0.2% is around the average for most true full-spectrum oils.

It has a ratio of:

  • 0.19 minor cannabinoids and terpenes for every 1 mg of CBD.

This is slightly above the average. Keep in mind that there’s a chance we’re underreporting the terpene-content and this ratio is even higher.

Transparency-wise Charlotte’s Web is almost as transparent as it gets. The only thing that’s missing from their lab-test reports is the terpene-profile.

Value-wise the Original Formula oil scores slightly higher than the average.

You get 17.65mg CBD per dollar and 3.1mg of minor cannabinoids and terpenes per dollar.

Buy CW Original Formula Oil

Full Review Charlotte’s Web

Next up…

5. Lazarus Naturals Full-Spectrum, High-Potency Tincture (Most Affordable)

Lazarus Naturals full-spectrum high-potency tinctureLazarus Naturals is another great value-for-money brand.

Their full-spectrum oils all classify as true full-spectrum products.

They are more than a bunch of isolated cannabinoids put together. How can we verify this? By checking the cannabinoid- and terpene-profile. If an oil contains cannabinoids like CBC and CBT, it’s likely that it’s truly full-spectrum. Generally, these are not cannabinoids used to bolster CBD products.

If a product contains hemp-derived terpenes, it’s likely that it’s a true full-spectrum product as well.

You can look for terpenes like humulene, linalool and myrcene.

Terpenes can be added later to make the product look like a true full-spectrum product. So it’s not a foolproof method to verify whether a product is full-spectrum. Always check the cannabinoid-profile as well.

Let’s look at the stats of their high potency full-spectrum oil:

  • 5 different cannabinoids in detectable levels (5.99% CBD), and;
  • 6 different terpenes in detectable levels.

The number of detectable cannabinoids is the lowest on the list. The number of detectable terpenes is right around the average.

When we look at how many minor cannabinoids and terpenes you get per 1mg CBD, we see the following:

For every 1mg of CBD, you get 0.15mg of minor cannabinoids and terpenes.

This is around the average.

The ratio of CBD to minor cannabinoids + terpenes is lower than the other oils on the list.

Yet, where it more than makes up for it is value.

Lazarus Naturals is one of the best value-for-money CBD brands.

For every 1 dollar, you get 42.85mg CBD and 6.42mg of minor cannabinoids and terpenes.

As you can see, this is even better value than you get with R+R Medicinals oil.

You could argue that Lazarus Naturals is the best value for money CBD brand. We rate R+R Medicinals higher because their oils have a wider cannabinoid- and terpene-profile.

As explained, when rating CBD products, the:

  • cannabinoid-, and,
  • terpene-profile,

have the most weight in the final rating. And R+R Medicinals scores better on those metrics than Lazarus Naturals.

That said, you can’t go wrong with Lazarus Naturals either.

Buy Lazarus N. Full-Spectrum Tincture

Frequently Asked Questions About Full-Spectrum CBD Oil

What’s the Difference Between Full-Spectrum CBD Oil and Regular CBD Oil?

Regular CBD oil usually refers to an oil that only contains CBD.

As you know, the hemp plant contains a multitude of beneficial compounds.

Regular CBD oil only contains an isolated form of CBD.

Full-spectrum CBD oil contains all:

  • cannabinoids,
  • terpenes, and,
  • flavonoids,

naturally present in hemp plants.

You can compare regular CBD oil to a vitamin C pill, and full-spectrum CBD oil to blueberries. Blueberries contain vitamin C, but also hundreds of other beneficial compounds.

Is Full-Spectrum CBD the Best?

After reviewing cannabinoid products for 6+ years and based on various scientific studies…

We KNOW that full-spectrum CBD is the most effective way to take CBD.

Here’s why:

Not only do a lot of plant compounds have uniquely beneficial effects on their own…

But studies show that isolated plant-compounds never have the same effect as the complete spectrum of compounds inside a plant (5, 6).

Some studies have found something similar when it comes to CBD.

For example:

Research shows epilepsy patients who use full-spectrum CBD need 4-times less CBD than those using pure CBD. Full-spectrum CBD users also experience fewer side effects (7).

Other studies show that cannabinoids produce an ‘entourage effect’. They create unique effects when combined. Effects that wouldn’t be present when taking the cannabinoid alone (8, 9).

Animal research shows combining two ineffective doses of CBDA and THC produces a pain-reducing effect (10).

But the synergistic effects of cannabis compounds aren’t only between cannabinoids.

Some studies suggest that terpenes have an important role in cannabis plant synergy as well (11).

And when you think about it makes sense. Cannabinoid-profiles between different cannabis strains are pretty similar. Yet a lot of strains produce different effects. How? Well, terepene-profiles between cannabis strains can differ significantly. Terpenes most likely have an important role in the differences of experienced effects.

The bottom line:

For most people, a cannabinoid-, terpene-rich full-spectrum CBD oil will be most effective.

Who Should Avoid Full-Spectrum CBD Oil?

Anyone that wants to avoid THC should avoid full-spectrum CBD oil.

Full-spectrum CBD products always contain small and legal amounts of THC.

And while small amounts of THC improve the effectiveness of CBD products, some people are:

  • Subjected to regular drug tests, and/or;
  • Are highly sensitive to THC.

In both cases, it would be best to avoid full-spectrum CBD products.

Even though full-spectrum CBD products contain only little THC…

When taken regularly over long periods of time, this small amount can be high enough for you to fail a drug test.

If you take a full-spectrum CBD oil and you start feeling a buzz or other side effects like:

  • anxiety, or,
  • paranoia,

it’s very likely that you’re highly sensitive to THC.

The best option for these two categories of people is broad-spectrum CBD oil.

Broad-spectrum CBD oil is THC-free. But it contains other hemp-derived cannabinoids and terpenes that act synergistically with CBD.

What’s Next…

Go  to our CBD Hub to learn more about CBD-related topics.

Scientific References:

    1. Samarut, R., Nixon, J., Kundap, U. P., Drapeau, P., & Ellis, L. D. (2019). Single and Synergistic Effects of Cannabidiol and Δ-9-Tetrahydrocannabinol on Zebrafish Models of Neuro-Hyperactivity. Frontiers in Pharmacology, 10. Published. https://doi.org/10.3389/fphar.2019.00226
    2. King, K. M., Myers, A. M., Soroka-Monzo, A. J., Tuma, R. F., Tallarida, R. J., Walker, E. A., & Ward, S. J. (2017). Single and combined effects of Δ9-tetrahydrocannabinol and cannabidiol in a mouse model of chemotherapy-induced neuropathic pain. British Journal of Pharmacology, 174(17), 2832–2841. https://doi.org/10.1111/bph.13887
    3. Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology, 163(7), 1344–1364. https://doi.org/10.1111/j.1476-5381.2011.01238.x
    4. Bertoli, A., Tozzi, S., Pistelli, L., & Angelini, L. G. (2010b). Fibre hemp inflorescences: From crop-residues to essential oil production. Industrial Crops and Products, 32(3), 329–337. https://doi.org/10.1016/j.indcrop.2010.05.012
    5. Rasoanaivo, P., Wright, C. W., Willcox, M. L., & Gilbert, B. (2011). Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions. Malaria Journal, 10(S1). https://doi.org/10.1186/1475-2875-10-s1-s4
    6. Kraus, B., Wolff, H., Heilmann, J., & Elstner, E. F. (2007). Influence of Hypericum perforatum extract and its single compounds on amyloid-β mediated toxicity in microglial cells. Life Sciences, 81(11), 884–894. https://doi.org/10.1016/j.lfs.2007.07.020
    7. Pamplona, F. A., da Silva, L. R., & Coan, A. C. (2018). Potential Clinical Benefits of CBD-Rich Cannabis Extracts Over Purified CBD in Treatment-Resistant Epilepsy: Observational Data Meta-analysis. Frontiers in Neurology, 9, 1. https://doi.org/10.3389/fneur.2018.00759
    8. Ben-Shabat, S., Fride, E., Sheskin, T., Tamiri, T., Rhee, M. H., Vogel, Z., . . . Mechoulam, R. (1998). An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. European Journal of Pharmacology, 353(1), 23–31. https://doi.org/10.1016/s0014-2999(98)00392-6
    9. Nahler, G. (2019b). Cannabidiol and Contributions of Major Hemp Phytocompounds to the “Entourage Effect”; Possible Mechanisms. Alternative, Complementary & Integrative Medicine, 5(2), 1–16. https://doi.org/10.24966/acim-7562/100066
    10. Rock, E. M., Limebeer, C. L., & Parker, L. A. (2018). Effect of cannabidiolic acid and ∆9-tetrahydrocannabinol on carrageenan-induced hyperalgesia and edema in a rodent model of inflammatory pain. Psychopharmacology, 235(11), 3259–3271. https://doi.org/10.1007/s00213-018-5034-1
    11. Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology, 163(7), 1344–1364. https://doi.org/10.1111/j.1476-5381.2011.01238.x

Post last updated on: January 2, 2023

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Winston Peki

Reviewing vaporizers, growing supplies, CBD products and scientific articles about cannabis, cannabinoids, and vaping since 2012. Read more about Winston here. LinkedIn

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© Copyright www.herbonaut.com · All Rights Reserved. The content on this website is for informational purposes only and is not intended as medical advice. Medical advice should always be obtained from a qualified medical professional for any health conditions or symptoms associated with them. Every possible effort has been made in preparing and researching this material. We make no warranties with respect to the accuracy, applicability of its contents or any omissions.

Science Based

This article is based on scientific studies, written by Winston Peki and fact-checked by experts.

Inside this article, you can find references to peer-reviewed scientific studies. The numbers in the parentheses (1, 2, …) are clickable links to these peer-reviewed scientific studies. In some cases, the link will give you direct access to the study, while in other cases if you want to read the full study, you either have to pay the publisher a fee or find a free version of the study elsewhere.

Herbonaut is a review and discussion platform that highly values honesty, integrity, and objectivity. We always strive to highlight the benefits, as well as the risks of a specific product or service.

Any topic can be approached from various angles, at Herbonaut we strive to highlight all these angles and will often examine and compare research with contradicting results.

Affiliate Disclosure

When we recommend products we link out to them. Most of the time this will be through an affiliate link. If you decide to buy a product through our affiliate links, we may earn a commission at no extra cost to you. By using these links, we can continue to grow this website by testing new products and writing new articles/reviews, and keep the website ad-free.

In no way do these affiliate links influence the products that we recommend. This website is first and foremost built on trust and honesty. We are 100% convinced that you’ll come to the same conclusion by following up on our advice. In case you feel our advice was not what you expected, please do contact us, as we would love to hear from you and have a friendly discussion with you about your experiences and findings!

Scientific References

Samarut, R., Nixon, J., Kundap, U. P., Drapeau, P., & Ellis, L. D. (2019). Single and Synergistic Effects of Cannabidiol and Δ-9-Tetrahydrocannabinol on Zebrafish Models of Neuro-Hyperactivity. Frontiers in Pharmacology, 10. Published. https://doi.org/10.3389/fphar.2019.00226

King, K. M., Myers, A. M., Soroka-Monzo, A. J., Tuma, R. F., Tallarida, R. J., Walker, E. A., & Ward, S. J. (2017). Single and combined effects of Δ9-tetrahydrocannabinol and cannabidiol in a mouse model of chemotherapy-induced neuropathic pain. British Journal of Pharmacology, 174(17), 2832–2841. https://doi.org/10.1111/bph.13887

Russo, E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology, 163(7), 1344–1364. https://doi.org/10.1111/j.1476-5381.2011.01238.x

Bertoli, A., Tozzi, S., Pistelli, L., & Angelini, L. G. (2010b). Fibre hemp inflorescences: From crop-residues to essential oil production. Industrial Crops and Products, 32(3), 329–337. https://doi.org/10.1016/j.indcrop.2010.05.012

Rasoanaivo, P., Wright, C. W., Willcox, M. L., & Gilbert, B. (2011). Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions. Malaria Journal, 10(S1). https://doi.org/10.1186/1475-2875-10-s1-s4

Kraus, B., Wolff, H., Heilmann, J., & Elstner, E. F. (2007). Influence of Hypericum perforatum extract and its single compounds on amyloid-β mediated toxicity in microglial cells. Life Sciences, 81(11), 884–894. https://doi.org/10.1016/j.lfs.2007.07.020

Pamplona, F. A., da Silva, L. R., & Coan, A. C. (2018). Potential Clinical Benefits of CBD-Rich Cannabis Extracts Over Purified CBD in Treatment-Resistant Epilepsy: Observational Data Meta-analysis. Frontiers in Neurology, 9, 1. https://doi.org/10.3389/fneur.2018.00759

Ben-Shabat, S., Fride, E., Sheskin, T., Tamiri, T., Rhee, M. H., Vogel, Z., . . . Mechoulam, R. (1998). An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. European Journal of Pharmacology, 353(1), 23–31. https://doi.org/10.1016/s0014-2999(98)00392-6

Nahler, G. (2019b). Cannabidiol and Contributions of Major Hemp Phytocompounds to the “Entourage Effect”; Possible Mechanisms. Alternative, Complementary & Integrative Medicine, 5(2), 1–16. https://doi.org/10.24966/acim-7562/100066

Rock, E. M., Limebeer, C. L., & Parker, L. A. (2018). Effect of cannabidiolic acid and ∆9-tetrahydrocannabinol on carrageenan-induced hyperalgesia and edema in a rodent model of inflammatory pain. Psychopharmacology, 235(11), 3259–3271. https://doi.org/10.1007/s00213-018-5034-1

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