Some small studies suggest that CBD may help with anxiety (1, 2).
But CBD isn’t the only anxiety-reducing compound that comes from hemp plants. Hemp plants contain various anxiolytic cannabinoids and terpenes (3, 4).
Based on:
- experience,
- several studies, and,
- well-established principles among herbalists and natural/holistic health professionals,
it’s likely that combining other hemp compounds with CBD may work better than CBD on its own (5).
For example:
Low doses of THC may have anxiety-reducing and anti-depressant effects as well.
Thus our list of CBD oils for anxiety consists mostly of ‘full-spectrum’ CBD oils.
A small percentage of CBD users will be sensitive to ‘THC’ or undergo regular drug tests. For those, we have listed a high-quality THC-free option.
Updated October 2026: We re-checked every product’s lab reports, prices and availability, and added Lazarus Naturals and cbdMD. We also toned down a few statements that went further than the research supports, and the full-spectrum picks carry a note on the US federal hemp law that takes effect on 11 December 2026. We’ve also added a summary of the research on CBD for anxiety, stress and mood.
Keep reading!
Table of Contents
Comparison of the Best CBD Oils for Anxiety
| Product |
NuLeaf Naturals
 |
NuLeaf Naturals
 |
Lazarus Naturals
|
Charlotte’s Web
 |
cbdMD
|
|---|---|---|---|---|---|
| Ranking | 1 | 2 | 3 | 4 | 5 |
| Ratings | 4.47/5 | 4.47/5 | 4.47/5 | 4.65/5 | 3.71/5 |
| CBD/$ | 0mg (14.1mg CBG) | 11.36mg | 37.5mg | 14.7mg | 15mg |
| Minor cannabinoids + terpenes/$ | 2mg | 1.5mg | 6.6mg | 3mg | 0.5mg |
| Cannabinoid-profileThe number of different cannabinoids present, and in what concentrations.: | |||||
| Terpene-profileThe number of different terpenes present, and in what concentrations: | |||||
| TransparencyBacked by 3rd-party lab-test reports? Transparent about where hemp is sourced?: | |||||
| ValueHow many CBD + minor cannabinoids and terpenes you get per dollar: | |||||
| Full-spectrum ratio | 0.14 | 0.13 | 0.17 | 0.19 | 0.03 |
| Read Review | NuLeaf Naturals | NuLeaf Naturals | Lazarus Naturals | Charlotte’s Web | cbdMD |
#1. NuLeaf Naturals CBG Oil (Best Mood-Enhancement Cannabinoid-Product)
Pros and Cons
- One of the only full-spectrum CBG oils
- Made from organic Hemp grown in Colorado
- CBG was less sedative than CBD in our experience, could be a better option for daytime
- No satisfaction-guarantee
- CBG is still relatively under-researched compared to CBD
- Could be too stimulating for nighttime
Cannabinoid-profile
Update October 2026: NuLeaf’s CBG Oil now costs $55.49 for 900mg and $62.87 for 1800mg (checked October 20, 2026). NuLeaf now also sells a THC-free CBD + CBG oil, Clarity Broad Spectrum Oil.
Although CBG isn’t the same as CBD…
I assume that you’re looking for the right cannabinoid-based product for anxiety. Thus you shouldn’t rule out other cannabinoids.
Here’s why:
Hemp contains many different cannabinoids, and CBD is only one of them.
And while CBG has much less scientific backing when it comes to anxiety…
One early study, presented at a 2006 cannabinoid research conference, suggested CBG may have antidepressant-like effects (10). There are also plenty of anecdotal reports suggesting that CBG may be useful for anxiety.
Our tests showed that CBG has stronger mood-elevating effects than CBD. CBG can be more stimulating and energizing than CBD.
Now:
Not everyone is looking for stimulating or energizing effects. During the night, taking too much CBG could interfere with your sleep routine.
But if you find CBD too sedative or want something more stimulating…
This CBG oil may suit you better than CBD.
For me, CBG has a slightly stimulating effect. But it wasn’t anything like coffee for example. It was a calm and centered stimulating effect, not jittery.
Still, I prefer to combine CBG with CBD in a 1:1 ratio.
As this is a full-spectrum hemp-extract, you also get a decent amount of CBD in it (0.13%). But the main compound is CBG (5.9%). This is a CBG-dominant product.
Everyone reacts slightly differently to cannabinoids.
But if you’ve tried CBD:
- without much effect, or,
- found it too sedating,
combining this CBG oil with your favorite CBD product, or even trying this alone, may yield positive results.
Heads-up: Under a 2025 US federal law, from 11 December 2026 hemp products may contain at most 0.4 mg THC per container (Congressional Research Service). Full-spectrum products like this one are expected to be affected. If you’re buying after that date, choose NuLeaf’s Clarity Broad Spectrum (THC-free) CBD + CBG oil instead.
Next up…
#2. NuLeaf Naturals CBD Oil (Best Customer-Rated CBD Oil for Anxiety)
Pros and Cons
- True full-spectrum product
- Made from organic Hemp grown in Colorado
- Best customer-rated CBD oil
- No satisfaction-guarantee
Cannabinoid-profile
It comes as no surprise:
Full-spectrum CBD products that come from transparent CBD brands dominate our product roundups.
And when we’re talking about full-spectrum oils…
NuLeaf Naturals full-spectrum CBD oil is one that you can’t ignore.
Here’s why:
When we look at customer reviews, this is the highest-rated CBD oil that we have ever come across.
In 6 years and 20.000+ reviews, NuLeaf Naturals CBD oil has gotten an average rating of 4.9 out of 5 stars.
When you look at NuLeaf Naturals’ third-party lab-test reports, you can see why.
This CBD oil has high levels of CBD, with their strongest bottle containing 4850 mg of CBD and a CBD percentage of 5.93%…
Plus, it contains many other hemp compounds like:
- THC,
- CBC,
- CBG, and,
- terpenes like beta-caryophyllene and alpha-humulene.
Some of these compounds have also been studied for anti-anxiety/antidepressant effects.
NuLeaf Naturals CBD oil doesn’t have any non-hemp anti-anxiety/anti-depressant compounds. But it does have the full spectrum of cannabinoids and terpenes. Some of them have been studied for anti-anxiety/antidepressant effects.
This oil is made from organic hemp and doesn’t contain ANY additives. It’s the purest hemp-extract on the list. Even the carrier oil is hemp-based (hemp-seed oil). This is the ‘hempiest’ of all CBD products.
Heads-up: Under a 2025 US federal law, from 11 December 2026 hemp products may contain at most 0.4 mg THC per container (Congressional Research Service). Full-spectrum products like this one are expected to be affected. If you’re buying after that date, choose NuLeaf’s broad-spectrum (THC-free) CBD oil instead.
Up next …
#3. Lazarus Naturals Organic CBD Tincture 50mg/mL (Best Value Full-Spectrum Oil)
Pros and Cons
- Best value on this list
- Batch lab reports from two accredited labs
- Assistance program for veterans and low-income households
- No terpene test
- No added botanicals
- Contains about 1.75mg THC per mL (see the note below)
New on this list in October 2026.
Lazarus Naturals is an Oregon brand that grows, extracts and bottles its own hemp. It publishes a certificate of analysis for each batch, and runs an assistance program with up to 60% off for veterans, people with long-term disabilities and low-income households.
Its Organic CBD Tincture contains 50mg of full-spectrum CBD per mL. A 30mL bottle (1,500mg) costs $40 and a 120mL bottle (6,000mg) costs $120 (checked October 20, 2026), which makes it the best value on this list by a wide margin.
The latest certificate of analysis on the product page (batch IC51, tested in August 2026 by SC Laboratories Oregon and Anresco Laboratories) shows per mL:
- 52mg CBD (the label says 50mg);
- 4.7mg CBG;
- 1.3mg CBC;
- 1.75mg THC.
Pesticides, heavy metals, residual solvents, yeast, mold and bacteria were all tested and within limits. There’s no terpene test, and unlike some oils on this list it has no added botanicals, so it’s a plain full-spectrum CBD oil.
How we rated this: the scores are based on Lazarus Naturals’ product page and its published certificate of analysis (batch IC51, August 2026), compared with the oils on this list that we’ve reviewed hands-on.
Heads-up: Under a 2025 US federal law, from 11 December 2026 hemp products may contain at most 0.4 mg THC per container (Congressional Research Service). Full-spectrum products like this one are expected to be affected. If you’re buying after that date, choose a THC-free oil instead, such as #5 cbdMD on this list or Lazarus Naturals’ THC-free CBD tincture (a CBD isolate at a much stronger 300mg per mL).
Click the button below to go to the Lazarus Naturals website:
#4. Charlotte’s Web Original Formula (Strong Full-Spectrum Option)
Pros and Cons
- One of the best full-spectrum products
- Charlotte’s Web controls the complete production process, including how the hemp plants are grown
- Consistent cannabinoid- and terpene-profiles between batches
- No terpene test
Cannabinoid-profile
Update October 2026: Charlotte’s Web has moved to a new website, and the button below now goes straight to the Original Formula oil there. Check the current price on their site.
Charlotte’s Web CBD oil is a true full-spectrum oil with many cannabinoids and terpenes. Not just a wide variety, but also in high concentrations.
Their ‘Original Formula’ is better in that regard as it’s ethanol-extracted. Ethanol extraction is one of the most effective extraction methods for preserving terpenes.
All other variables kept the same, like:
- hemp strain, and,
- growing conditions,
ethanol-extracted CBD products have the best cannabinoid- and terpene-profiles.
Of all full-spectrum CBD oils we’ve reviewed this one has the highest concentration of CBC (0.38%) . CBC is short for for ‘cannabichromene’ .
There’s no scientific evidence (yet) that shows CBC has anxiety-reducing effects. But there’s some anecdotal evidence on various forums like Reddit.
Whether CBC turns out to be another potent anxiety-reducing cannabinoid or not…
Having such a high levels of CBC can only be good for the effects of a CBD product. CBC could also make CBD’s anti-anxiety effects stronger.
Charlotte’s Web is one of the most transparent CBD brands.
Now:
All CBD oils on the list prove with lab-test reports that they’re contaminant-free.
But if you want an extra layer of assurance…
Charlotte’s Web is a producer that controls the whole manufacturing process. From planting the seed to shelving the final product.
During its production-cycle, a bottle of this oil is subject to 20 different quality control tests.
This is yet another great full-spectrum option for anxiety.
Heads-up: Under a 2025 US federal law, from 11 December 2026 hemp products may contain at most 0.4 mg THC per container (Congressional Research Service). Full-spectrum products like this one are expected to be affected. If you’re buying after that date, choose Charlotte’s Web’s THC-free CBD oil instead.
#5. cbdMD Broad Spectrum CBD Oil Tincture (Best THC-Free Option)
Pros and Cons
- No detectable THC
- Lab report for every batch via QR code
- Publicly traded company
- Low concentrations of other cannabinoids and terpenes
New on this list in October 2026. We reviewed this oil in our list of the best CBD oils; here’s the summary.
cbdMD’s tincture is the THC-free, broad-spectrum option on this list.
Although in low concentrations, it does contain some minor cannabinoids, like:
- CBG (0.03%);
- CBN (0.01%), and
- Hemp-derived terpenes, mainly limonene (0.08%).
Value-wise, this product is right around the average. One dollar gets you 15mg of CBD and 0.5mg of minor cannabinoids and terpenes.
cbdMD is a publicly traded company, which means it’s subject to more scrutiny and audits than a regular CBD company. Every product comes with a QR code that links to a third-party lab report, so you can check that your batch is free from THC and contaminants.
cbdMD’s broad-spectrum products are batch-tested to contain no detectable THC. cbdMD now also sells separate delta-9 THC products, so check that you’re buying the broad-spectrum tincture.
Click the button below to go to the cbdMD website:
How We Rate CBD Tinctures for Anxiety and Depression
Summarized, here’s what we’re looking for when we’re looking for a good CBD oil for anxiety:
- It should contain a full spectrum of hemp-derived cannabinoids and terpenes, and/or;
- It should contain one, or more non-hemp-derived anti-anxiety/depressant compounds, and;
- It should be easy to ingest above-average concentrations of CBD with it. This means a CBD concentration of at least 2%.
To learn exactly how we rate CBD products, please read our CBD products rating system.
What the Research Says About CBD for Anxiety, Stress and Mood
CBD isn’t an approved treatment for anxiety or depression. The research is still early, but for anxiety it’s more encouraging than for most other uses.
Anxiety
- Social anxiety: 24 people with social anxiety disorder took either 600 mg of CBD or a placebo before a simulated public-speaking test. The CBD group reported less anxiety, discomfort and trouble thinking clearly during their speech (11).
- The dose matters: in a similar test with 57 healthy men, 300 mg of CBD reduced anxiety while speaking, but 150 mg and 600 mg did not (12). More isn’t always better.
- Everyday use: in a case series of 72 adults at a psychiatric clinic, most taking 25 mg of CBD a day, anxiety scores fell in about 79% of patients in the first month and stayed lower. There was no placebo group, so some of that improvement may have happened anyway (13).
Stress
In a small crossover study with 9 healthy men, a single 600 mg dose of CBD lowered resting blood pressure and blunted the rise in blood pressure during stress tests (14). That’s the body’s physical stress response, not a measure of how stressed people felt.
Depression
CBD had fast antidepressant-like effects in mice, which seemed to depend on 5-HT1A serotonin receptors (15). Human trials are still scarce, so there’s no good evidence yet that CBD helps with depression.
The Bottom Line
CBD may take the edge off situational anxiety for some people, but it’s not a substitute for professional care. If you take antidepressants or anti-anxiety medication, talk to your doctor first, because CBD can interact with them (see CBD’s side effects and drug interactions).
Frequently Asked Questions About Using CBD Oil for Anxiety
How to Use CBD Oil for Anxiety/Depression?
Taking CBD oil or tinctures for anxiety should be taken as for any other purpose.
Orally ingesting CBD tinctures consists of two parts:
- Putting the drops under your tongue for 30-60 seconds (the sublingual method), and;
- Swallowing the drops after it.
If you follow these steps, the CBD will get absorbed in two ways:
- Through the mucous membranes beneath your tongue, avoiding the gastrointestinal tract, and;
- Through the gastrointestinal tract itself.
Since CBD isn’t very well absorbed through the digestive system, we recommend using it sublingually as well.
Learn more:
When to Take?
Everyone reacts differently to CBD.
But in my experience, taking CBD oil in the morning, right after breakfast, works best for me.
Never take CBD on an empty stomach.
How Much Should I Take?
Since CBD oil is not a medicine in the traditional sense, there are no official dosage guidelines.
Generally, we recommend starting with low doses and work your way up gradually. Start with the recommended dose from the manufacturer for a single serving.
Studies that looked at the effects of CBD on anxiety found results with large doses of 300-600mg of CBD. Keep in mind that these doses are based on CBD products. You might need a much smaller dose if you use a high-quality full-spectrum oil like the ones on our list.
When Can I Expect Results?
CBD oil is not a medicine. It’s uncertain whether it will provide you with any relief for your anxiety or depression.
But most people experience effects after 1-2 weeks of taking CBD daily.
What Are The Side Effects?
Taking CBD oil is not without risks. The biggest risks relates to potential interactions with traditional prescription medication.
CBD can interfere with the metabolization of various prescription drugs. If you’re on prescription drugs and want to use CBD, please consult with your doctor first.
There are also contamination risks related to taking CBD products. Products can be contaminated with:
- heavy metals,
- residual solvents,
- synthetic cannabinoids,
- bacteria,
- fungi,
- and pesticides.
If ingested over long periods of time, these toxins may worsen your anxiety symptoms.
If you want to learn more about preventing health risks related to CBD-use, click the link below:
Learn More About CBD
The Best CBD Oils: A list of our most recommended CBD oil brands, includes full-spectrum CBD oils, broad-spectrum CBD oils, and CBD isolates. All are 3th-party lab-tested to confirm they’re contaminant-free and contain high levels of CBD.
The Best CBD Gummies: A list of our recommended CBD gummies. All are 3th-party lab-tested to confirm they’re contaminant-free and contain high levels of CBD.
What Is CBD Oil?: How CBD oil is made, the different types, and what the research says so far.
The Best CBD Oils for Pain: Our picks for pain, plus a summary of the research on CBD and pain.
The Most Effective Form of CBD: How isolate, broad-spectrum and full-spectrum products compare, with their pros and cons.
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